Application of in silico and TTC based decision tree for safety assessment of botanicals
Safety assessment of botanicals has always been a challenge, not only due to the difficulties in defining them analytically, but also due to data gaps in traditional toxicology endpoints.
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Read-across – State of the art and next level!
In light of the limitations of existing non-animal based hazard assessment methodologies particularly for systemic endpoints, read-across is currently considered to be the most applicable strategy in the short- to medium-term in support of innovation.
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