The importance of having a solid PC data package to support human health/environmental risk assessment and read across under REACH

Dr. Thomas Petry

Evaluation of in vitro assays for the assessment of the skin sensitisation hazard of functional polysiloxanes and silanes

A published research programme investigating the skin sensitisation potential of a group of functional polysiloxanes and silanes in vivo and in vitro is an instructive example of what can happen in ‘real life’ when testing a group of chemical substances that seemingly belong to the same class of chemicals for skin sensitisation

Principles underlying the next generation risk assessment approach (NGRA)

Next Generation Risk Assessment (NGRA) is defined as an exposure-led, hypothesis-driven risk assessment approach that integrates in silico, in chemico and in vitro approaches.