Dr. Ann De Smedt

Dr. Ann De Smedt is a European Registered Toxicologist with more than 20 years of experience in pharmaceutical industry. She has extensive expertise in hazard identification, human health risk assessment and translational toxicology. In addition, Ann has experience in occupational toxicology, including the derivation Permitted Daily Exposure (PDE) values, occupational exposure limits (OELs) and establishment of cleaning limits.  At the regulatory level, she has substantial experience with pharmaceutical legislation and regulatory requirements associated with EMA and FDA and with REACH Regulation.
Before joining ToxMinds, Ann held senior scientific and leadership roles in pharmaceutical R&D, where she directed multidisciplinary teams and managed complex toxicology and regulatory projects from early scientific evaluation through to regulatory submission. Her experience includes in vitro, in vivo and in silico approaches, alternative test methods, omics technologies, GLP-accredited toxicology laboratories, and the translation of complex scientific data into practical recommendations for project teams and stakeholders.

Ann holds a PhD in Biological Sciences and is certified as a European Registered Toxicologist (ERT). She combines strong scientific judgement with pragmatic project leadership, supporting clients with strategic toxicological advice across pharmaceuticals, chemicals and cosmetics.

Languages: Dutch, English, French

CONTACT

Dr. Ann De Smedt
Managing Consultant

Phone: +32 (0)2 762 91 45
Email: contact me

SPECIALITIES

Pharmaceuticals, Chemicals, Cosmetics

Regulatory strategy, Translational toxicology, Hazard identification, REACH, Occupational exposure limits, PDE/MACO calculations, Alternative test methods, Omics technologies, In vitro / in vivo / in silico approaches