News from ECHA’s Committee for Risk Assessment (RAC) – Adoption of Opinion on Harmonised Classification and Labelling for MWCNTs
For hazards of highest concern (e.g., carcinogenicity, mutagenicity, reproductive toxicity), the European harmonised classification and labelling (CLH) system is set […]
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Nanomaterials in cosmetics – The next priority of the Commission?
Since a number of new developments have taken place in the area of nanomaterial safety research, the EC Scientific Committee […]
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Requirement of second species testing for evaluating developmental toxicity potential
Over the last decade, there has been ongoing debate on the regulatory requirement of a second-species testing requirement to identify developmental toxicity. A recent article by Braakhuis et al. (2019) has questioned the reproducibility of developmental toxicity results and the comparison approach using NOAELs. The current insight attempts to present the state-of-the-art information on the ongoing discussion.
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Severity of eye effects caused by accidental exposure to detergent and cleaning products
A most interesting study concerning the severity of eye effects caused by accidental exposure to detergent and cleaning product has recently been published by Scazzola et al., 2019. The study investigated the predictivity of a product’s classification for eye hazard following reported accidental human exposures to common household detergent and cleaning products.
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Are you ready for the upcoming deadline for the poison centre notifications of hazardous mixtures?
Importers and downstream users placing hazardous mixtures will have to provide specific information in a harmonized notification format to the relevant national appointed bodies, who will make this information available to poison centres so that they can provide rapid medical advice in the event of an emergency.
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ECHA Public activities coordination tool
A new version of the Public activities coordination tool (PACT) has been integrated in the European Chemicals Agency (ECHA) website. This searchable and customizable database now includes substances for which dossier evaluation is ongoing and registries of CLP/restriction/SVHC intentions.
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13th SETAC Scientific Symposium: Extrapolation of effects across biological levels
The symposium discussed extrapolation tools for environmental risk assessment purposes across different biological levels, and more importantly, how to bring those models to regulatory conformity.
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Establishing health-based exposure limits (PDE) for pharmaceutical actives
ToxMinds established, in line with EMA guidance, permitted daily exposures for more than 30 active pharmaceutical ingredients to allow managing any API residues in case of shared facility manufacturing arrangement.
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Consortium management and technical support to European REACH and Biocides consortia
ToxMinds is the consortium management organisation and technical lead consultancy for 3 REACH and 1 Biocides consortia
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REACH strategy and registration support to chemical manufacturers
With more than 250 REACH registrations over the last 8 years, ToxMinds is trusted by its clients in the REACH registration process.
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